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 The Dynamic Implications of Treating Baldness ... by Elle

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Elle
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PostSubject: The Dynamic Implications of Treating Baldness ... by Elle   Wed Apr 14, 2010 8:19 pm

The MSN Video stream from The Today Show as originally posted (www.onlinecliniqueforum.forumotion.com) and discussed in the year '2008, is now 'defunct' -- so p;ease scroll down to see additional posts regarding most recent research updates ... in a bit more detail, etc....

*************************************************************************
"--In 2008, Matt Lauer and NBC Chief Medical Editor Dr. Nancy Snyderman reported on a potential baldness ‘cure’ discovered by University of Pennsylvania Medical Center Researchers.

The new technology (Penn U) involves Stem Cells and a new Complex (not yet disclosed) that acts to generate/stimulate New (and potentially unlimited) Follicle Generation in research mice (other hair growth treatments work to stimulate growth in existing follicles, not lost follicles and cannot generate new follicles or growth once gone, and unlike other treatments, this protocol is expected to work for everyone). Human trials are expected to begin in the near future, with the treatment available, in as little as 3-5 years.--"

Good luck, best regards, -Elle.
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PostSubject: Re: The Dynamic Implications of Treating Baldness ... by Elle   Sat Apr 26, 2014 3:41 pm

2014-
Although the early research seemed to indicate that hair multiplication/cloning trials were imminent, we have yet to see any firm progress in this newer technology regarding hair
restoration.

However, there are a number of methods being researched at this time and hopefully will come to fruition soon as hair multiplication would make hair restoration surgery a reality for all patients, including those who currently are not considered
as candidates for treatment due to lack of donor hair (cloning or/and multiplication would allow an infinite number of follicles to be produced including the possibility of foreign donor hair being made available to patients with total hairloss (alopecia areata, totalis, universalis, or severe injury (burns, etc.)...).

And although it seems to be taking much longer than anticipated, it does appear to be a technology worth watching as we move forward in researching all possible baldness cures.

Informational forums with surgeon reviews and cloning and hair multiplication and current FUT hair restoration surgery and other hair restoration technology research in the pipeline can be sourced (online) at:

Hairrestorastionnetwork.com
Baldingblog.com


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PostSubject: Re: The Dynamic Implications of Treating Baldness ... by Elle   Fri Apr 17, 2015 7:06 pm

Arrow MSNBC 2015 -- Hair Multiplication?? Update Arrow
------------------------------------------------------------


MSNBC follow-up investigators reported that researchers (Dr. Angela Christiano, et., al.) at Columbia university announced that they are currently researching Potential Hair ‘Regenration’ through 1) Human-Papilla Extraction, Multiplication and Re-injection...

The process utilizes three primary steps:
1. Extraction of human papilla cells from scalp
2. Culture the extended cells in lab (using 3-D culture method /
   hanging-drop method) to grow or multiply additional number
   of cells for re-implantation/injection.
3. Re-inject cells back into scalp to induce growth of (new)
   hair…

To date, the hairs that were grown in on human skin grafted onto lab mice did grow hair, albeit it appeared that up to /less than 22% of the critical genes for hair growth were activated in this process. Although additional research and methods/protocol testing is needed to determine if these hairs can develop into full-on terminal hairs as in a full head of hair.

But, this new approach, if successful would broaden the scope of patients who would be eligible for hair restoration. And other countries are testing stem-cell based multiplication using elements of this technique (although there are risks with stem cell therapy that are not present in the Christiano-method, so hopefully the research will bear fruit in the long term).. So it seems there is some progress in this area, albeit much slower than the projected time line as announce 5 years ago.

----------
And
2). Researchers at Sanford-Burnham Medical Research Institute (Dr. Alexey Terskikh et., al.) announced research through the use of Pluripotent Stem Cells (modified or manipulated) to create New dermal papillae cells capable of initiating human hair growth. Although the concerns over the use of stem cell technology is based in the potential risk for uncontrolled cellular changes/mutations (cancer??) that gene manipulation can trigger, whereas Notably, no-such-risk with the Christiano method of simply extracting and multiplying existing human-Papilla-cells from the scalp and then simply re-injecting them as being researched at Columbia U...


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PostSubject: Re: The Dynamic Implications of Treating Baldness ... by Elle   Fri Aug 26, 2016 11:24 am

2016
Belgravia Centre (UK) Announces Planned Launch of (Pluripotent) Stemcell Based Cure!

See Full Article Here:
http://www.belgraviacentre.com/blog/shiseido-partners-with-replicel-to-launch-hair-loss-cure-in-2018/
---------------
In short:
The main point of the research is that they have successfully developed a method of replicating follicles from pre-existing mature-stem-cells, "as extracted from a few donor hairs at the root of the scalp and then converted to dermal papilla cells, using the stem cells," (Belgravia). This provides the potential for infinite number of cells to be generated in the lab and re-introduced to the patient's recipient scalp area, which will develop into full functional hairs over time!-- The planned initial launch of the treatment protocol has been pushed back from 2016 to 2018.

As with any treatment, it is best to only allow a double board certified and licensed medical doctor, who is a hairloss specialist (in good standing) to perform this type of procedure at a reputable outpatient clinic or hospital, (as aesteticians and spa technicians are not necessarily medically qualified professionals).

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